In recent years, GLP-1 medicines Have a lot of traction. They not only help manage type 2 diabetes. They also play an important role in helping people lose weight. But now, Recent research It suggests that these medicines can also help to protect the brain from scientific decline.
Two new published Observatory studies It has been found that people taking GLP-1 medicines are at risk of dementia growth, including Alzheimer’s disease and its academic disorders. These results, though initially, give rise to new hope in weight loss doctors and patients.
Let’s see what these studies have found and what it means for the future of dementia prevention.
What are GLP-1 medicines for weight loss?
GLP-4 is a class of medicines that was actually prepared to treat type 2 diabetes. They work by imitating the role of the GLP-1 hormone in the body, which helps regulate blood sugar levels, suppress appetite and slowly digest. Famous GLP-1 are included in weight loss medicines Semaglotide (Sold under the names of Ozampk and Weagovo), Lerglotide (Sexanda), and others.
Recently, these drugs have focused on their effectiveness in protecting mental health.
New studies: closely look
1. Meta -analysis of 26 random trials
A group of researchers and medical students at the University of Gala, Ireland, organized 26 random clinical trials to assess the role of GLP -1 RAS and other diabetes in reducing the risk of dementia and academic disorders.
GLP -1 drugs received a significant reduction (45 % less opportunity) in the risk of dementia growth.
2. Electronic Health Record Review
The second study analyzed the records of more than 100,000 real -world patients from a large health database. This study has also shown that in the people who started treating the GLP-1, about 3333 % of the dementia was less than those who did not get these medicines.
How does the GLP-1 weight loss medicines benefit the brain?
Although the correct procedure of how GLP-1 weight loss medicines is benefited is not completely clear to the brain, researchers have some theories:
- Reduces inflammation: GLP-4 can reduce chronic inflammation, which plays a role in both diabetes and neurodegenerative diseases.
- Improves blood flow: By improving heart health, GLP 1 weight loss medicines can increase blood flow to the brain.
- Weight and provides metabolic control: Obesity, insulin resistance, and high blood sugar are the risk factors of dementia. By controlling them, these weight loss medicines can indirectly protect mental health.
- Neuroprotective Action: Some studies suggest that GLP-1 medicines for weight loss can work directly to the brain to protect and improve the function.
Should you start taking GLP-1 drugs for mental health?
Not yet.
Mass, random control OK and Auk+ trials There are still continuing, both are watching the effects of semaglotide on the mild academic malfunction (MCI). The purpose of these studies is to find out if the drug can reduce the increase in Alzheimer’s disease.
The results are expected by the end of 2025, and if they confirm what the observational studies are suggesting, it can open a new issue of use for GLP-1 drugs in neurology.
While the idea promises, GLP-1 medicines:
- They are not approved for the prevention or treatment of dementia,
- It may have side effects (such as nausea, gastrointestinal problems, and abnormal cases, pancreatic inflammation), and
- They are expensive, especially if not covered by insurance.
If you have already suggested GLP-1 medicines for weight loss and diabetes, the potential advantage of the brain can be an extra bonus. But it is not recommended to start merely to prevent dementia, at least until further research confirms its effect.
As usual, talk to a board certified obesity medical physician like Dr. Mona Lala before considering a GLP-1 for weight loss or diabetes.
Fix the appointment time Today, for a personal consultation and find out if the GLP-1 medicines can be right for you or your loved one.
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